Scientists Find New Genetic Link for Autism and Schizophrenia

Despite all the years of research that have gone into them, cognitive conditions like autism and schizophrenia are still largely a mystery. Heres one nice step toward figuring them out, though: Researchers from UCLA have discovered a specific genetic trait in a small community in Finland that might have some clues.There are communities in northern Finland that have been extremely isolated from the outside world for years. So many rare genes and genetic defects are more common in those populations. One in particular had a high rate of autism, schizophrenia, and other cognitive conditions. After examining data from 173 participants in that community, compared to 1586 from the rest of Finland, it was found that a chromosome 22 deletion was present in 18 of the 173 compared to just one in the larger sample.With a sample of 173, could the overrepresentation of this deletion be an unrelated manifestation of such a small genetic pool? In other words, are these just specific to the particular to the region? Its not likely, actually. Chromosome 22 deletion affects the creation of an enzyme called TOP3β, which helps translate DNA into RNA. Its still up in the air exactly how this works to disrupt brain development, but theres a clear link between TOP3β and conditions like schizophrenia and fragile X.RELATEDScientists Find First Definitive Genetic Links to AutismScientists have uncovered several gene mutations that sharply increase the chances of developing autism. Its the first time researchers have… Read…Theres still a long way to go, but this is good news, since every small step toward figuring this stuff out is good news. [Nature via New Scientist]

via Scientists Find New Genetic Link for Autism and Schizophrenia.


About steventorresramos

I have over (24) years of Computer Aided Drafting & Design experience and over (16) years of IT experience. After graduating high school I attended a Technical College and earned an Associate Degree in Drafting & Design. I then enrolled at the University of Puerto Rico where I earned an A.S. in Civil Engineering Technologies. While attending the Univ. of Puerto Rico I worked as a freelance Drafter for a variety of architects and engineers. During my senior year I began to work for the firm Planning Management & Development in Ponce, Puerto Rico. Two years later I was offered the position at Mario Corsino & Associates, which later became InterGroup a medium size Civil Engineering, Architectural and Planning firm in Bayamon, Puerto Rico. At InterGroup I became assistant chief drafter where I was responsible for 20+ drafters & civil techs, and this is also where I began my IT training. In 2000 I decided to move to St. Petersburg, FL where I was hired as CAD Manager at Advanced Engineering & Design a small Civil Engineering firm established in 1998. Currently still employed by Advanced Engineering & Design I’m now the CAD/IT Manager. I have also continued to expand my knowledge base in both the IT & CADD fields through continued training, certifications, and attending Autodesk University. I’m currently an Autodesk Certified Professional proficient in AutoCAD, Civil 3D and various other Autodesk products. I have been the President of the Tampa Bay Autodesk Users Group (TBAUG) since late 2007 and a member of Autodesk Users Group International (AUGI) since 1996. I have an A.S. Degree in Computer Networking , a Bachelors of Applied Science in Technology Management and currently finishing work on my Masters in Computer Information Systems. I’m a licensed drafter in the US Commonwealth of Puerto Rico, and a Microsoft Certified Professional. I hold certificates as a Microsoft Certified IT Professional: Server Administrator, Cisco Networking Associate Professional and Linux Administrator.
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